A PARP inhibitor with the potential for treating certain types of prostate cancer

What is Lynparza?

Lynparza is a PARP inhibitor that was originally developed in the 1990s and is currently used to treat ovarian cancer.

Who is developing Lynparza?

Lynparza was developed by the pharmaceutical company AstraZeneca.

What have AstraZeneca discovered so far?

In 2020, results from a phase 3 clinical trial found that patients with advanced prostate cancer which has spread outside the prostate, and who have genetic variants in BRCA1, BRCA2 and ATM, lived longer and spent more time without their cancer getting worse when they took Lynparza.

To find out more about what genetic variants are click here.

At what stage of development is Lynparza?

The positive outcome of this clinical trial led to Lynparza being approved in the USA and the EU. It is currently being considered for approval in England.

To find out more about the typical timescales involved in developing new drugs and more information about clinical trials please click here.

How can I find out more?

You can find out more about Lynparza here.

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